GTA 6’s expansive world isn’t just about flashy cars and big heists — it’s about survival, adaptability, and knowing when to switch between firepower. Whether you’re navigating chaotic street fights, tight indoor raids, or long-range pursuits, your weapon loadout matters more than ever. A balanced setup can make the difference between dominating a mission or constantly respawning at the nearest hospital.
Below are 9 versatile and effective weapon combos every GTA 6 player should consider when crafting a well-rounded loadout.
1. Assault Rifle + Pump Shotgun
The classic combo never fails. The assault rifle gives you mid-range control, while the pump shotgun is your go-to for clearing rooms. It’s great for players who move aggressively through missions or gang encounters.
2. SMG + Compact Grenade Launcher
Perfect for urban warfare. The SMG handles well in close-quarter battles with a fast rate of fire, and the compact launcher gives you the edge against vehicles or clustered enemies.

3. Sniper Rifle + Silenced Pistol
This one’s for stealth builds. Pick off enemies from a distance, then switch to a silenced pistol for close-in cleanup without triggering alarms. Great for infiltration missions or solo contract work.
4. Carbine Rifle + Combat Knife
For those who like to stay quick on their feet. The carbine rifle offers precision and control, and the knife is a silent, backup weapon perfect for quick stealth takedowns when ammo runs low.
5. Heavy MG + Molotov Cocktails
Use the MG to lay down suppressive fire and the Molotovs to control crowd flow or set up traps. This combo thrives in holdout situations like ambushes or base defenses.
6. Tactical SMG + Tear Gas
For players who like to keep enemies on their heels. Tear gas flushes enemies from cover, and the tactical SMG’s mobility lets you clear the aftermath quickly. It’s highly effective in tight alleyways and buildings.
7. Marksman Rifle + Sawed-Off Shotgun
Marksman rifles are great for semi-auto precision, and when enemies close the gap, the sawed-off finishes the job. A deadly pairing in bounty missions or dynamic PvP scenarios.
8. Carbine Rifle Mk II + Sticky Bombs
This is a favorite among veteran players. The Mk II’s customization options make it highly versatile, while sticky bombs let you prepare for ambushes or take out pursuing vehicles. This combo also works well in missions with multiple objectives across the map.
9. Advanced Rifle + Flashbangs
For players running squad support or tackling high-difficulty heists, this combo provides utility and firepower. Flashbangs can disorient tough enemies, giving you the edge to push forward with accurate rifle bursts.
Weapon Combo Strategy Tips
When choosing your combo, always consider your mission type, enemy density, and personal playstyle. Some players prefer close-range chaos, while others take a surgical approach. The key is adaptability. Loadouts that work in one scenario can leave you vulnerable in another.
If you find yourself short on cash when trying to unlock or upgrade these weapons, many players opt to buy gta 6 money to stay ahead. Those on Xbox platforms may prefer to buy gta 6 money xbox one specifically. Platforms like U4N offer options when in-game grind time is limited but performance still matters.
Balanced weapon combos give you tactical flexibility and confidence in any situation. Whether you’re chasing bounties, holding down objectives, or just causing mayhem in Los Santos’ underworld, the right loadout can make your session smoother and more rewarding.
Experiment with your own combinations, learn what feels right, and don’t forget to rotate depending on your objective. In GTA 6, preparation is just as valuable as aim.